Ignet

Gene Pair: IGF1, CTGF

Related Sentences

#	PMID	Sentence
1	11422741	Immunohistology indicated that CTGF was expressed in renal cortex of diabetic rats, in contrast to controls in some tubular cross-sections, particularly dilated-appearing proximal tubules, in which it tended to colocalize with insulin-like growth factor-I (IGF-I).
2	11422741	CTGF has an IGF-binding domain and binds to IGF-I.
3	11422741	In NRK-49F cells, IGF-I increased the activity of CTGF towards the expression of Col alpha1III.
4	11422741	CTGF is expressed and regulated downstream from TGF-beta and HGF in proximal tubular cells, is induced by diabetic rat glomerular ultrafiltrate, and has moderate profibrogenic activity in tubular cells and renal interstitial fibroblasts, where its activity is IGF-I dependent.