|
Gene Pair Information
Gene Pair: IL6, COL1A1
Related Sentences
# |
PMID |
Sentence |
1 |
21169360
|
In human mesangial cells (a microvascular pericyte that secretes excess collagen in diabetic glomerulosclerosis), ET-1 increased mRNA and protein for MCP-1 (macrophage chemoattractant protein-1) and IL-6.
|
2 |
21169360
|
Exogenous addition of either recombinant MCP-1 or IL-6 increased collagen accumulation by 3.5-fold.
|
3 |
21169360
|
Co-stimulation with both MCP-1 and IL-6 did not elevate collagen accumulation further.
|
4 |
21169360
|
Taken together, these results demonstrate that an autocrine signaling loop involving MCP-1 and IL-6 contributes to ET-1-induced collagen accumulation.
|
5 |
21649785
|
The expression of interleukin-6, myeloperoxidase, stromelysin-1, and collagenase-3 was increased in the GT of diabetic rats on Day 10, while the expression of type I collagen and elastin was decreased.
|
|