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Gene Pair Information

Gene Pair: IL6, COL1A1

Related Sentences

# PMID Sentence
1 21169360 In human mesangial cells (a microvascular pericyte that secretes excess collagen in diabetic glomerulosclerosis), ET-1 increased mRNA and protein for MCP-1 (macrophage chemoattractant protein-1) and IL-6.
2 21169360 Exogenous addition of either recombinant MCP-1 or IL-6 increased collagen accumulation by 3.5-fold.
3 21169360 Co-stimulation with both MCP-1 and IL-6 did not elevate collagen accumulation further.
4 21169360 Taken together, these results demonstrate that an autocrine signaling loop involving MCP-1 and IL-6 contributes to ET-1-induced collagen accumulation.
5 21649785 The expression of interleukin-6, myeloperoxidase, stromelysin-1, and collagenase-3 was increased in the GT of diabetic rats on Day 10, while the expression of type I collagen and elastin was decreased.