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Gene Pair Information
Gene Pair: INS, CYSLTR2
Related Sentences
# |
PMID |
Sentence |
1 |
21958333
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Both the GPCR agonist AR231453 and the novel bile acid mimetic INT-777 have been shown to stimulate GLP-1 release, leading to increased insulin secretion and improved glucose tolerance in mice.
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2 |
19679549
|
Insulin enhanced GPCR signaling through a rapamycin-sensitive mTOR-dependent pathway.
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3 |
19679549
|
Metformin pretreatment completely abrogated insulin-induced potentiation of Ca(2+) signaling but did not interfere with the effect of GPCR agonists alone.
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4 |
19679549
|
Insulin also enhanced GPCR agonist-induced growth, measured by DNA synthesis, and the number of cells cultured in adherent or nonadherent conditions.
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