Ignet

Gene Pair: INS, HADH

Related Sentences

#	PMID	Sentence
1	7050060	HADH activity was increased in the normal and diabetic insulin-treated trained groups, but because of its already high activity in the diabetic diaphragm, it did not require an adaptation.
2	15894466	To determine the underlying mechanisms of these metabolic malfunctions, we studied mitochondrial respiration, uncoupled respiration and oxidative enzyme activities (citrate synthase (CS), 3-hydroxy-acyl-CoA-dehydrogenase activity (HAD)) before and after acute exposure to insulin and/or palmitate in myotubes established from healthy lean and obese subjects and T2D patients.
3	17491019	This study examines HADHSC expression in purified rat beta cells and investigates whether its selective suppression elevates insulin release.
4	20923481	In the present study, we investigated the mechanism underlying HADHSC-mediated regulation of insulin secretion.
5	20923481	Knockdown of HADHSC increased both fuel- (glucose or leucine plus glutamine) and non-fuel (high KCl)-induced insulin secretion.
6	20923481	Enhanced glucose-stimulated insulin secretion (GSIS) induced by HADHSC knockdown was independent of changes in cytosolic Ca(2+) and also occurred in the presence of fatty acids.
7	20923481	Insulin secretion promoted by both fuel and non-fuel stimuli is negatively regulated by HADHSC.