Ignet

Gene Pair: IRS2, FOXO3

Related Sentences

#	PMID	Sentence
1	21933986	ChIP assays indicated that transcription factors FoxO1 and FoxO3a associated with the IRE on the IRS-2 promoter in ?-cells in a PI3K/PKB-dependent manner, whereas others, such as SREBP-1, the transcription factor binding to immunoglobulin heavy chain enhancer 3', and the aryl hydrocarbon receptor nuclear translocator (ARNT), did not.
2	21933986	The molecular mechanism for feedback control of IRS signaling to decrease IRS-2 expression in liver and ?-cells is quite distinct, with a predominant role played by FoxO3a in ?-cells.