Ignet

Gene Pair: LEP, IGF1

Related Sentences

#	PMID	Sentence
1	14510911	Leptin correlated to kilogram fat mass in both women (r=0.55, P<0.001) and men (r=0.47, P=0.003), but in contrast, there were no significant correlations between GHBP and fat mass and GHBP and IGF-I, either in women or in men (all, r<0.24, P>0.2).
2	14525912	Leptin treatment corrected the fasting-induced growth deficiency, but further reduced the level of serum IGF-I.
3	14525912	These results indicate that leptin stimulates growth even in the presence of caloric restriction independently of peripheral IGF-I.
4	15447907	We investigated the effects of IGF-I, dehydroepiandrosterone sulfate, and sex steroids on body composition and fat distribution and the effects of these hormones and leptin on total body bone mineral content (TBMC) and volumetric bone mineral density (vBMD) at the femoral neck and lumbar spine (LS) in 255 healthy children (137 girls), aged 7-8 y.
5	18779578	These findings suggest that leptin reverses the catabolic consequences of total lack of insulin, potentially by suppressing glucagon action on liver and enhancing the insulinomimetic actions of IGF-1 on skeletal muscle, and suggest strategies for making type 1 diabetes insulin-independent.
6	19029226	Despite the increase in circulating leptin levels, there was no change in IGF1, IGF2, free IGF1, or IGF-binding proteins during the 2-month treatment period.