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Gene Pair Information
Gene Pair: MAPK1, ADIPOQ
Related Sentences
# |
PMID |
Sentence |
1 |
20802255
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At the molecular level, adiponectin decreased high glucose-induced accumulation of intracellular reactive oxygen species and consequently suppressed activation of p38 MAP kinase (MAPK) and expression of the senescence marker p16(INK4A).
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2 |
20339310
|
The prolonged treatment of mature 3T3-L1 adipocytes with palmitate, a kind of saturated free fatty acid, reduced adiponectin expression at both mRNA level and protein level, accompanied with the enhanced phosphorylation of PKC? and extracellular signal-regulated kinase (ERK), and the impaired expression of peroxisome proliferator-activated receptor ?2 (PPAR?2) mRNA.
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3 |
20339310
|
Either PD98059, an ERK inhibitor or PKC? pseudosubstrate, a specific PKC? inhibitor, restored palmiate-inhibited PPAR?2 mRNA expression and subsequent adiponectin expression.
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