Ignet

Gene Pair Information

Gene Pair: MAPK1, COL1A1

Related Sentences

#	PMID	Sentence
1	12709399	A substantial inhibition of AGE-induced Smad activation and collagen synthesis by ERK/p38 MAPK inhibitors, but not by TGF-beta blockade, suggests that the MAPK-Smad signaling crosstalk pathway is a key mechanism in diabetic scarring.
2	15780081	Inhibition of p38(mapk) or p42/44(mapk) activities did not affect LDL-induced TGF-beta1, CTGF, and collagen I expression, whereas inhibition of c-Jun NH2-terminal kinase (JNK) suppressed LDL-induced TGF-beta, CTGF, and collagen I expression.
3	18726071	The expression of collagen types I and III regulated by AGEs through MAPK was partly reversed after treatment with TRB3 siRNA.
4	15692059	Finally, to determine whether BK stimulates CTGF, TGF-betaRII, and collagen I expression via activation of MAPK pathways, MC were pretreated with an inhibitor of p42/p44 MAPK (PD-98059) for 45 min, followed by BK (10(-8) M) stimulation for 24 h.
5	15692059	Selective inhibition of p42/p44 MAPK significantly inhibited the BK-induced increase in CTGF, TGF-betaRII, and collagen I levels.
6	21573155	Therefore, we investigated the signaling cross-talk by which p38 MAPK mediates wound healing in fibroblasts cultured on native collagen and 3DG-collagen.
7	21573155	Furthermore, proliferation and collagen production in fibroblasts cultured on native collagen was dependent on p38 MAPK regulation of AKT and ERK1/2.
8	21573155	In contrast, 3DG-collagen decreased fibroblast migration, proliferation, and collagen expression through ERK1/2 and AKT downregulation via p38 MAPK.
9	21439910	We also found that oxLDL-IC stimulated collagen IV expression by engaging Fc gamma receptor (Fc?R) I and III, but not Fc?RII, and that p38 MAPK, JNK and PKC pathways were involved in collagen IV expression.
10	22005299	In human platelets, aldose reductase synergistically modulated platelet response to both hyperglycemia and collagen exposure through a pathway involving ROS/PLC?2/PKC/p38? MAPK.