Ignet

Gene Pair: MAPK1, GADD45B

Related Sentences

#	PMID	Sentence
1	16528573	The aim of this study was to investigate if Gadd45b prevents IL-1beta-induced beta cell MAPK signalling and apoptosis.
2	16528573	The effects of Gadd45b expression on signalling by JNK, ERK and p38 were assessed by Western blotting and kinase assays.
3	16528573	In INS-1E and beta-TC3 cells, expression of Gadd45b inhibited IL-1beta-induced activation of JNK and ERK, but augmented IL-1beta-mediated p38 activity.
4	16528573	Inadequate induction of Gadd45b, which encodes a novel beta cell JNK and ERK inhibitor, may in part explain the pro-apoptotic response of beta cells to IL-1beta.