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Gene Pair Information
Gene Pair: MMP2, LEP
Related Sentences
# |
PMID |
Sentence |
1 |
15983226
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Incubation of HASMCs with leptin enhanced the proliferation and MMP-2 expression in these cells and increased the generation of intracellular reactive oxygen species (ROS).
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2 |
15983226
|
In HASMCs, leptin induced PKC, extracellular signal-regulated kinase (ERK)1/2, and nuclear factor-kappaB (NF-kappaB) activation and inhibition of these signaling pathways abrogated HASMC proliferation and MMP-2 expression induced by this hormone.
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3 |
15983226
|
Metformin also inhibited the effect of leptin on HASMC proliferation and MMP-2 expression.
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