Ignet

Gene Pair: PNPLA2, INS

Related Sentences

#	PMID	Sentence
1	16380488	In 3T3-L1 adipocytes, insulin decreased ATGL and increased adiponutrin expression in a dose- and time-dependent manner, suggesting that insulin directly mediates this nutritional regulation.
2	16380488	These data suggest that murine ATGL but not adiponutrin contributes to net adipocyte lipolysis and that ATGL and adiponutrin are oppositely regulated by insulin both in vitro and in vivo.
3	21498783	We hypothesized that an imbalance of ATGL relative to HSL (expression or activity) may contribute to DAG accumulation and insulin resistance.
4	21644917	Insulin also suppresses lipolysis by down-regulating the expression of the rate-limiting lipolytic enzyme, adipose triglyceride lipase or ATGL.
5	21709540	This work indicates the potential link of ATGL with the pathogenesis of insulin resistance and T2DM.