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Gene Pair Information
Gene Pair: PTEN, SPARC
Related Sentences
| # | PMID | Sentence |
| 1 | 20929508 | The results suggest the following molecular etiopathophysiology of DN: (i) hyperglycemia upregulates IGF2, which initiates PTEN, a regulator of IGF2 signaling; (ii) loss of this IGF2-PTEN feedback loop causes changes that are characteristic of DN; and (iii) lowered expression of the repair modulator SPARC results in the development and/or progression of DN. |