Ignet

Gene Pair: SIRT1, SHC1

Related Sentences

#	PMID	Sentence
1	21778425	Objective: In this study, we investigated the role of SIRT1, a class III histone deacetylase, in the regulation of p66Shc expression and hyperglycemia-induced endothelial dysfunction.
2	21778425	However, knockdown of p66Shc significantly reversed the effects of SIRT1 knockdown.
3	21778425	Our findings indicate that repression of p66Shc expression by SIRT1 contributes to the protection of hyperglycemia-induced endothelial dysfunction.