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Gene Pair Information
Gene Pair: SMAD3, INS
Related Sentences
# |
PMID |
Sentence |
1 |
18951876
|
In this study, human insulin promoter was activated by Smad2, Smad3 and the pancreatic and duodenal homeobox factor-1 (PDX-1) in the ALK7 pathway.
|
2 |
19265200
|
Transduction of adenoviral Smad3 into primary human and non-human primate islets suppresses insulin content, whereas, dominant-negative Smad3 enhances insulin levels.
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3 |
21270259
|
Transforming growth factor-?/Smad3 signaling has been implicated in various metabolic processes, including adipogenesis, insulin expression, and pancreatic ?-cell function.
|
4 |
21270259
|
Smad3-knockout mice exhibited diminished adiposity with improved glucose tolerance and insulin sensitivity.
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