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Gene Pair Information

Gene Pair: SMAD3, INS

Related Sentences

# PMID Sentence
1 18951876 In this study, human insulin promoter was activated by Smad2, Smad3 and the pancreatic and duodenal homeobox factor-1 (PDX-1) in the ALK7 pathway.
2 19265200 Transduction of adenoviral Smad3 into primary human and non-human primate islets suppresses insulin content, whereas, dominant-negative Smad3 enhances insulin levels.
3 21270259 Transforming growth factor-?/Smad3 signaling has been implicated in various metabolic processes, including adipogenesis, insulin expression, and pancreatic ?-cell function.
4 21270259 Smad3-knockout mice exhibited diminished adiposity with improved glucose tolerance and insulin sensitivity.