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Gene Pair Information

Gene Pair: STAT3, POMC

Related Sentences

# PMID Sentence
1 17023536 We find that Pomc expression is diminished in the mutant mice, suggesting that Stat3 is required for Pomc transcription.
2 17023536 These results demonstrate a requirement for Stat3 in transcriptional regulation of Pomc but indicate that this circuit is only one of several components that underlie the neuronal response to leptin and the role of Stat3 in that response.
3 20068134 Upregulation of Socs3 in POMC neurons leads to impairment of STAT3 and mammalian target of rapamycin (mTOR)-S6K-S6 signaling, with subsequent leptin resistance, obesity, and glucose intolerance.