Ignet

Gene Pair: VHL, INS

Related Sentences

#	PMID	Sentence
1	21029313	Several recent studies have shown that Vhl deletion in ?-cells results in Hif1? activation, impaired glucose-stimulated insulin secretion (GSIS) and glucose intolerance.
2	21242957	We generated ?-cell-specific VHL-knockout mice using the Cre-loxP recombination system driven by the rat insulin promoter to assess the role of VHL in glucose homeostasis and ?-cell function.
3	21242957	VHL deletion in the pancreatic ?-cells led to impaired glucose tolerance due to defects in glucose-stimulated insulin secretion and ?-cell mass with age.