Ignet

Gene Pair: XBP1, INS

Related Sentences

#	PMID	Sentence
1	20349222	Prolonged XBP1s production hampers beta cell function via inhibition of insulin, Pdx1 and Mafa expression, eventually leading to beta cell apoptosis.
2	21784843	We have used an insulin-secreting cell line with inducible expression of dominant negative (DN) HNF1?, a transcription factor vital for correct ?-cell development and function, to show that HNF1? is required for Xbp1 transcription and maintenance of the normal ER stress response.