Ignet

Gene Pair: NPHS1, RARA

Related Sentences

#	PMID	Sentence
1	19474283	In this report, we investigated roles of the retinoic acid receptor (RAR), the retinoid X receptor (RXR) and the vitamin D receptor (VDR) in the regulation of the nephrin gene.
2	19474283	Reporter podocytes were treated with agonists and/or antagonists of RAR, RXR or VDR, and activities of the nephrin gene promoter, the retinoic acid response element (RARE) and the vitamin D response element (VDRE) were evaluated.
3	19474283	The nephrin gene promoter was also activated by these agents, which was mediated by RAR and VDR, but unexpectedly, not by RXR.
4	19474283	ATRA-triggered, RAR-mediated activation of the nephrin gene promoter was not suppressed by the VDR antagonist.
5	19474283	In contrast, the 1,25(OH)(2)D(3)-triggered, VDR-mediated activation of the nephrin gene promoter was significantly suppressed by the RAR antagonist, but not by RXR antagonists.