Ignet

Gene Pair: NPHS1, TRPC6

Related Sentences

#	PMID	Sentence
1	21471003	Furthermore, nephrin, an adhesion protein between the foot processes of podocytes, binds to phosphorylated TRPC6 via its cytoplasmic domain, competitively inhibiting TRPC6-PLC-?1 complex formation, TRPC6 surface localization, and TRPC6 activation.
2	21471003	Importantly, FSGS-associated mutations render the mutated TRPC6s insensitive to nephrin suppression, thereby promoting their surface expression and channel activation.