Gene Information
Gene symbol: CDH1
Gene name: cadherin 1, type 1, E-cadherin (epithelial)
HGNC ID: 1748
Synonyms: uvomorulin, CD324
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BRCA1 | 1 hits |
| 2 | BRCA2 | 1 hits |
| 3 | CHEK2 | 1 hits |
| 4 | MUTYH | 1 hits |
| 5 | PALB2 | 1 hits |
| 6 | PTEN | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 33724863 | We used panel sequencing containing 22 high/moderate-risk susceptibility genes and parallel MLPA analysis of BRCA1/2, CHEK2 genes, to analyze 94 individuals with a strong family/personal history of breast and/or ovarian cancer. |
| 2 | 33724863 | We used panel sequencing containing 22 high/moderate-risk susceptibility genes and parallel MLPA analysis of BRCA1/2, CHEK2 genes, to analyze 94 individuals with a strong family/personal history of breast and/or ovarian cancer. |
| 3 | 33724863 | In total, we have identified 22 causal DNA variants (23.4%) showing 15 primary findings in BRCA1/2 genes (68.2%) and 7 positive secondary findings in CHEK2, PALB2, CDH1, and MUTYH genes (31.8%). |
| 4 | 33724863 | In total, we have identified 22 causal DNA variants (23.4%) showing 15 primary findings in BRCA1/2 genes (68.2%) and 7 positive secondary findings in CHEK2, PALB2, CDH1, and MUTYH genes (31.8%). |
| 5 | 33724863 | Besides known mutations, the BRCA1 variant c.2794del (p.Val932Leufs*68) and variant c.2480dup (p.Tyr827*) in the CDH1 gene represent the novel, previously unpublished variants that might be population-specific. |
| 6 | 33724863 | Besides known mutations, the BRCA1 variant c.2794del (p.Val932Leufs*68) and variant c.2480dup (p.Tyr827*) in the CDH1 gene represent the novel, previously unpublished variants that might be population-specific. |
| 7 | 35323371 | To evaluate the clinical implications related to the timing, we conducted a chart review on a cohort of women (<i>N</i> = 276) with high-risk (<i>BRCA1</i>, <i>BRCA2</i>, <i>CDH1</i>, <i>PTEN</i> and <i>TP53</i>) and moderate high-risk (<i>ATM</i> and <i>CHEK2</i>) predisposition to breast cancer in a 48-month follow up. |