Gene Information
Gene symbol: CNBP
Gene name: CCHC-type zinc finger, nucleic acid binding protein
HGNC ID: 13164
Synonyms: RNF163, ZCCHC22, CNBP1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | PARP1 | 1 hits |
| 2 | SREBF1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 33738458 | Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. |
| 2 | 33738458 | Through multi-omics profiling we show that PARP inhibitors enhance both anti- and pro-tumor features of macrophages through glucose and lipid metabolic reprogramming driven by the sterol regulatory element-binding protein 1 (SREBP-1) pathway. |
| 3 | 33738458 | Combined PARP inhibitor therapy with CSF-1R blocking antibodies significantly enhanced innate and adaptive anti-tumor immunity and extends survival in BRCA-deficient tumors <i>in vivo</i> and is mediated by CD8<sup>+</sup> T-cells. |