Gene Information
Gene symbol: GADD45A
Gene name: growth arrest and DNA-damage-inducible, alpha
HGNC ID: 4095
Synonyms: GADD45
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BRCA1 | 1 hits |
| 2 | DDB2 | 1 hits |
| 3 | TP53 | 1 hits |
| 4 | XPC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11709053 | Oligonucleotide array-based expression profiling identified a number of genes that were upregulated at various times following inducible expression of BRCA1 including the DNA damage-responsive gene GADD45 (Growth Arrest after DNA Damage). |
| 2 | 12195423 | Mutations in the TP53 tumor-suppressor gene are found in 70-80% of BRCA1-mutated breast cancer but only 30% of those with wildtype BRCA1 (ref. 3). |
| 3 | 12195423 | Here we show that BRCA1 specifically enhances the GGR pathway, independent of p53, and can induce p53-independent expression of the NER genes XPC, DDB2, and GADD45. |