Gene Information
Gene symbol: PSMD9
Gene name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
HGNC ID: 9567
Synonyms: p27, Rpn4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL2 | 1 hits |
| 2 | CCND1 | 1 hits |
| 3 | CDKN1A | 1 hits |
| 4 | CTSD | 1 hits |
| 5 | EGFR | 1 hits |
| 6 | ERBB2 | 1 hits |
| 7 | ESR1 | 1 hits |
| 8 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9581822 | To characterize the biological features of breast cancer associated with germ-line mutations in BRCA1 and BRCA2, invasive tumors were studied from 58 Jewish women ascertained through studies of early-onset breast cancer. |
| 2 | 9581822 | All women were tested for the BRCA1 founder mutations 187delAG (commonly known as 185delAG) and 5385insC (commonly known as 5382insC) and the BRCA2 founder mutation 6174delT. |
| 3 | 9581822 | There were no differences between the two groups in the frequency of expression of epidermal growth factor receptor, cathepsin D, bcl-2, p27, p53, or cyclin D. |
| 4 | 11250681 | Extensive studies of BRCA1- and BRCA2-associated breast tumours have been carried out in the few years since the identification of these familial breast cancer predisposing genes. |
| 5 | 11250681 | The morphological studies suggest that BRCA1 tumours differ from BRCA2 tumours and from sporadic breast cancers. |
| 6 | 11250681 | Studies to date have investigated issues such as steroid hormone receptor expression, mutation status of tumour suppressor genes TP53 and c-erbB2, and expression profiles of cell cycle proteins p21, p27 and cyclin D1. |
| 7 | 11250681 | BRCA1-associated tumours appear to show an increased frequency of TP53 mutations, frequent p53 protein stabilization and absence of imunoreactivity for steroid hormone receptors. |
| 8 | 11250681 | Further studies of larger number of samples of both BRCA1- and BRCA2-associated tumours are necessary to clarify and confirm these observations. |