Gene Information

Gene symbol: TGFB1

Gene name: transforming growth factor, beta 1

HGNC ID: 11766

Synonyms: CED, TGFbeta

Related Genes

# Gene Symbol Number of hits
1 CCL2 1 hits
2 COL1A1 1 hits
3 COL4A4 1 hits
4 HSPG2 1 hits
5 IL7 1 hits
6 MIF 1 hits
7 PDGFB 1 hits
8 TGFA 1 hits

Related Sentences

# PMID Sentence
1 9176840 Mouse glomerular epithelial cells in culture with features of podocytes in vivo express aminopeptidase A and angiotensinogen but not other components of the renin-angiotensin system.
2 9176840 By indirect immunofluorescence, the cells were positive for cytokeratin, vimentin, desmin, and the ZO-1 protein, a component of the tight junction complex.
3 9176840 The mRNA expression of several components of the renin-angiotensin system was also examined, and some factors indirectly coupled to the renin-angiotensin system component angiotensin II in this podocytic culture by RT-PCR analysis. mRNA Expression for the angiotensin II degrading hydrolase aminopeptidase A and angiotensinogen was found, but this was not found for any other component of this system, such as renin, angiotensin-converting enzyme, or the angiotensin II receptors AT1a, AT1b, and AT2.
4 9176840 In addition, expression of the growth factors transforming growth factor-beta and interleukin-7, and the extracellular matrix components fibronectin, laminin B2, perlecan, and collagen IV alpha 1, was observed.
5 9371576 In the above cells, persistent infection induced the de novo synthesis of platelet-derived growth factor A/B and enhanced the release of transforming growth factor beta1/2.
6 9513903 Six-hour stimulation of mesangial cells with interferon-gamma or platelet-derived growth factor significantly increased MIF mRNA levels.
7 9513903 However, the addition of recombinant MIF to mesangial cells did not affect mesangial cell proliferation or constitutive transforming growth factor-beta mRNA expression, nor did MIF induce monocyte chemoattractant protein-1 mRNA expression.
8 10571774 Role for transforming growth factor-beta1 in alport renal disease progression.
9 11073824 Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy.
10 11073824 Alport syndrome is a genetic disorder resulting from mutations in type IV collagen genes.
11 11316849 On day 100, glomerulosclerosis, tubulointerstitial damage, glomerular and interstitial accumulation of types III and IV collagen, and overexpression of transforming growth factor-beta were widespread.