Gene Information
Gene symbol: EGFR
Gene name: epidermal growth factor receptor
HGNC ID: 3236
Synonyms: ERBB1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTB | 1 hits |
| 2 | BCL2 | 1 hits |
| 3 | BRCA1 | 1 hits |
| 4 | BRCA2 | 1 hits |
| 5 | CTSD | 1 hits |
| 6 | EGF | 1 hits |
| 7 | ERBB2 | 1 hits |
| 8 | HRAS | 1 hits |
| 9 | MYC | 1 hits |
| 10 | PSMD9 | 1 hits |
| 11 | TGFA | 1 hits |
| 12 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8910495 | Several observations suggest the 180-kDa protein is the epidermal growth factor (EGF) receptor: (i) C-20 reacted avidly with a 180-kDa protein immunoprecipitated by an antibody to the EGF receptor; (ii) an EGF receptor antibody detected a 180-kDa protein immunoprecipitated by C-20; (iii) the affinity purified EGF receptor was both immunoprecipitated and detected on immunoblots by the C-20 antibody but not another BRCA1 antibody; (iv) similar phosphopeptide maps were generated from the EGF receptor and the 180-kDa protein immunoprecipitated by C-20, and this peptide map was distinct from the 220-kDa phosphoprotein; and (v) the C-20 immunizing peptide bears sequence identity to the EGF receptor. |
| 2 | 9096675 | Cross-reaction between antibodies raised against the last 20 C-terminal amino acids of BRCA 1 (C-20) and human EGF and EGF-R in MCF 10a human mammary epithelial cell line. |
| 3 | 9205094 | These findings indicate that the products of BRCA1, neu, and erbB breast cancer genes participate in a common or shared signaling pathway important in cell growth and its regulation. |
| 4 | 9504854 | Fourteen cases of DCIS and 11 of DCIS with minimal invasion were analysed for mRNA levels of beta-actin, EGFR, c-cerbB2, MTS1, k-ras, RB, BRCA1, cyclin E, and c-myc genes. |
| 5 | 9581822 | To characterize the biological features of breast cancer associated with germ-line mutations in BRCA1 and BRCA2, invasive tumors were studied from 58 Jewish women ascertained through studies of early-onset breast cancer. |
| 6 | 9581822 | All women were tested for the BRCA1 founder mutations 187delAG (commonly known as 185delAG) and 5385insC (commonly known as 5382insC) and the BRCA2 founder mutation 6174delT. |
| 7 | 9581822 | There were no differences between the two groups in the frequency of expression of epidermal growth factor receptor, cathepsin D, bcl-2, p27, p53, or cyclin D. |
| 8 | 9618944 | They also express the BRCA-1, erbB2, and EGF receptor genes and possess the H-ras, K-ras, and p53 genes. |
| 9 | 10066082 | Possible molecular prognostic markers are: BRCA-1, BRCA-2, p53, erbB oncogenes, loss of heterozygosity (LOH), chromosomal aberrations, microsatellite instability, transforming growth factor alpha (TGFalpha), and the multiple drug resistance (MDR) gene. |