Gene Information
Gene symbol: HRAS
Gene name: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
HGNC ID: 5173
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTB | 1 hits |
| 2 | APC | 1 hits |
| 3 | ATM | 1 hits |
| 4 | BRCA1 | 1 hits |
| 5 | BRCA2 | 1 hits |
| 6 | CDKN2A | 1 hits |
| 7 | EGF | 1 hits |
| 8 | EGFR | 1 hits |
| 9 | ERBB2 | 1 hits |
| 10 | ESR1 | 1 hits |
| 11 | MYC | 1 hits |
| 12 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8007694 | Perturbations of oncogenes in breast carcinoma include amplifications of the HER-2/neu and PRAD1 genes, as well as p53 mutations. |
| 2 | 8007694 | Such germline abnormalities may occur at the BRCA1, H-RAS VNTR, and p53 loci. |
| 3 | 8950667 | A family history of pancreatic adenocarcinoma is not common in patients with this disease, but recent research has shown that pancreatic adenocarcinoma can be a feature of cancer susceptibility syndromes associated with germline mutations in p16, BRCA1, BRCA2, and APC. |
| 4 | 8950667 | Somatic mutations in p16, BRCA2, and APC have also been reported in pancreatic cancer; however, K-RAS mutations appear to be the commonest oncogenic alteration. |
| 5 | 8987214 | Two genes associated with a high breast cancer risk (BRCA1 and BRCA2) have been discovered recently from study of large breast-cancer-dense kindreds. |
| 6 | 8987214 | Nevertheless, it appears that about 1 to 2 per cent of all breast cancer may be due to rare deleterious mutations in BRCA1 or BRCA2. |
| 7 | 8987214 | There may be more common mutations in other genes (such as ATM, HRAS1) that confer a moderate risk of breast cancer, and may account for 5 to 15 per cent of cases. |
| 8 | 9164266 | Three genes have now been identified that confer increased susceptibility in families with a clear hereditary (i.e., Mendelian) pattern of expression: BRCA1, BRCA2 and p53. |
| 9 | 9164266 | Some evidence is available to implicate three additional genes that fit this category: AT, ESR and HRAS1. |
| 10 | 9504854 | Fourteen cases of DCIS and 11 of DCIS with minimal invasion were analysed for mRNA levels of beta-actin, EGFR, c-cerbB2, MTS1, k-ras, RB, BRCA1, cyclin E, and c-myc genes. |
| 11 | 9618944 | They also express the BRCA-1, erbB2, and EGF receptor genes and possess the H-ras, K-ras, and p53 genes. |