Gene Information

Gene symbol: JUN

Gene name: jun proto-oncogene

HGNC ID: 6204

Synonyms: c-Jun, AP-1

Related Genes

# Gene Symbol Number of hits
1 BRCA1 1 hits
2 GADD45A 1 hits
3 MAPK8 1 hits
4 MAPK9 1 hits

Related Sentences

# PMID Sentence
1 10367887 Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.
2 10367887 A major BRCA1 target is the DNA damage-responsive gene GADD45.
3 10367887 Induction of BRCA1 triggers apoptosis through activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK), a signaling pathway potentially linked to GADD45 gene family members.
4 10367887 The p53-independent induction of GADD45 by BRCA1 and its activation of JNK/SAPK suggest a pathway for BRCA1-induced apoptosis.