Gene Information
Gene symbol: KRT122P
Gene name: keratin 122 pseudogene
HGNC ID: 30197
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BRCA1 | 1 hits |
| 2 | BRCA2 | 1 hits |
| 3 | TOP2A | 1 hits |
| 4 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9781655 | To determine whether there are any molecular markers that might help explain this paradox between pathologically aggressive neoplasms in patients with HBC and the lack of extreme clinically aggressive disease, we studied several molecular parameters in a group of 34 breast cancer patients with mutations in either the BRCA1 or BRCA2 tumor suppressor genes and compared them with a group of 20 breast cancer patients with non-HBC. |
| 2 | 9781655 | To determine whether there are any molecular markers that might help explain this paradox between pathologically aggressive neoplasms in patients with HBC and the lack of extreme clinically aggressive disease, we studied several molecular parameters in a group of 34 breast cancer patients with mutations in either the BRCA1 or BRCA2 tumor suppressor genes and compared them with a group of 20 breast cancer patients with non-HBC. |
| 3 | 9781655 | In general, patients with HBC had tumors that were of higher nuclear grade, contained a higher population of proliferating cells, showed increased expression of DNA topoisomerase II-alpha (topo II-alpha), lacked hormone receptors, and were more likely to show immunopositivity for the p53 tumor suppressor gene. |
| 4 | 9781655 | In general, patients with HBC had tumors that were of higher nuclear grade, contained a higher population of proliferating cells, showed increased expression of DNA topoisomerase II-alpha (topo II-alpha), lacked hormone receptors, and were more likely to show immunopositivity for the p53 tumor suppressor gene. |