Gene Information

Gene symbol: PMS1

Gene name: PMS1 postmeiotic segregation increased 1 (S. cerevisiae)

HGNC ID: 9121

Related Genes

# Gene Symbol Number of hits
1 MHS2 1 hits
2 MLH1 1 hits
3 MSH2 1 hits
4 PMS2 1 hits

Related Sentences

# PMID Sentence
1 9538124 Studies have shown that these diseases may be associated with mutations in a number of tumor suppressor genes, mainly BRCA1 and BRCA2.
2 9538124 HNPCC-ovarian cancer associated families reveal frequent mutations in at least four genes (hMSH2, hMLH1, hPMS1, and hPMS2) involved in the repair of mismatched DNA.
3 9616736 This interest has been heightened by recent discoveries that germ-line mutations such as BRCA1 and BRCA2 in hereditary breast cancer are responsible for an increasing percentage of common solid tumors.
4 9616736 At least four mutator genes (MHS2, MLH1, PMS1 and PMS2) appear to account for 70-80% of hereditary nonpolypoid colorectal cancer (HNPCC).