Gene Information
Gene symbol: SAMSN1
Gene name: SAM domain, SH3 domain and nuclear localization signals 1
HGNC ID: 10528
Synonyms: NASH1, SASH2, SH3D6B, HACS1, SLy2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BRCA1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8942979 | In addition, BRCA1 contains two nuclear localization signals and localizes to the nucleus of normal cells. |
| 2 | 8942979 | Any one of four germ-line mutations in the C-terminal region found in patients with breast or ovarian cancer (Ala-1708-->Glu, Gln-1756 C+, Met-1775-->Arg, Tyr-1853 ->Stop), had markedly impaired transcription activity. |
| 3 | 8955125 | In an attempt to elucidate the potential mechanism for the nuclear transport of BRCA1 protein, three regions of highly charged, basic residues, 503KRKRRP508, 606PKKNRLRRKS615, and 651KKKKYN656, were identified as potential nuclear localization signals (NLSs). |
| 4 | 8955125 | Consistently, hSRP1alpha (importin-alpha), a component of the NLS receptor complex, was identified in a yeast two-hybrid screen using BRCA1 as the bait. |