Gene Information

Gene symbol: LBP

Gene name: lipopolysaccharide binding protein

HGNC ID: 6517

Synonyms: BPIFD2

Related Genes

# Gene Symbol Number of hits
1 CD14 1 hits
2 TNF 1 hits

Related Sentences

# PMID Sentence
1 1724447 The 52 kD myeloid membrane glycoprotein CD14 represents the receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein (LBP); it is involved in LPS induced tumor necrosis factor-alpha production.
2 1724447 The effect of rIFNg on CD14 in PBL cultures was dose-dependently inhibited by rIL-4 and this inhibition is probably due to an IL-4 mediated blockade of IFNg secretion.
3 1724447 The results, showing that CD14 antigen expression is upregulated by LPS and downregulated by rIFNg and rIL-4, suggest that the LPS-LBP receptor is involved in the feedback response of IFNg and IL-4 to LPS stimulation.