Gene Pair Information
Gene Pair: BRCA1P1, BRCA2
Related Sentences
| # | PMID | Sentence |
| 1 | 33476590 | Patients carrying mutations in breast cancer susceptibility genes like BRCA1 and BRCA2 (BRCA1/2) account for 5-10% of all breast cancer patients. |
| 2 | 33476590 | Four novel variants (BRCA2 L1390W, BRCA2 Glu432fs, BRCA1 P706L, and BRCA1 Cys882fs) were identified. |
| 3 | 33476590 | BRCA2 Glu432fs decreased the expression of BRCA2 protein, enhanced cell migration and invasion ability, and prevented the protein from interacting with RAD51, resulting in a defect in the homologous recombination pathway. |
| 4 | 33775137 | High-risk women can be identified by a mutation detection in predisposing gene like BRCA1 or BRCA2. |