Gene Pair Information
Gene Pair: ERBB2, PSMD9
Related Sentences
| # | PMID | Sentence |
| 1 | 11250681 | Extensive studies of BRCA1- and BRCA2-associated breast tumours have been carried out in the few years since the identification of these familial breast cancer predisposing genes. |
| 2 | 11250681 | The morphological studies suggest that BRCA1 tumours differ from BRCA2 tumours and from sporadic breast cancers. |
| 3 | 11250681 | Studies to date have investigated issues such as steroid hormone receptor expression, mutation status of tumour suppressor genes TP53 and c-erbB2, and expression profiles of cell cycle proteins p21, p27 and cyclin D1. |
| 4 | 11250681 | BRCA1-associated tumours appear to show an increased frequency of TP53 mutations, frequent p53 protein stabilization and absence of imunoreactivity for steroid hormone receptors. |
| 5 | 11250681 | Further studies of larger number of samples of both BRCA1- and BRCA2-associated tumours are necessary to clarify and confirm these observations. |