Gene Pair Information
Gene Pair: MKI67, BRCA1
Related Sentences
| # | PMID | Sentence |
| 1 | 38279496 | Lacking protein functions of Breast cancer susceptibility gene1 (BRCA1) and Breast cancer susceptibility gene2 (BRCA2), by methylation, represents tissue-specific silent epigenetic regions that tolerate genomic instability and may end in different cancers, mainly breast and ovary. |
| 2 | 38279496 | The extracted DNA was subjected to methylation-specific PCR (MSP) to determine the promoter methylation status of BRCA1 and its correlation with study parameters including protein expression level of ER, PR, Her2/neu, and Ki67 receptors. |
| 3 | 38279496 | Compared with negative methylation, positive BRCA1 promoter methylation was significantly high among triple negative (ER-, PR-, Her2-) cases with high proliferative index. |