Gene Pair Information
Gene Pair: CD2, NPHS1
Related Sentences
| # | PMID | Sentence |
| 1 | 10997929 | CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere. |
| 2 | 10997929 | CD2-associated protein (CD2AP) is an adapter molecule that can bind to the cytoplasmic domain of nephrin, a component of the glomerular slit diaphragm. |
| 3 | 10997929 | Mice lacking CD2AP exhibit a congenital nephrotic syndrome characterized by extensive foot process effacement, suggesting that CD2AP-nephrin interactions are critical to maintaining slit diaphragm function. |
| 4 | 10997929 | We have examined the patterns of expression of both CD2AP and nephrin in developing mouse and human kidney. |
| 5 | 10997929 | Kidneys from Cd2ap -/- mice initially exhibited normal nephrin localization, but as the mice aged and foot processes became effaced, nephrin disappeared. |
| 6 | 10997929 | In laminin-beta(2) mutant mice exhibiting nephrotic syndrome, CD2AP in glomeruli was aberrantly localized in a primarily punctate pattern. |
| 7 | 11195047 | CD2-associated protein and the kidney. |
| 8 | 11195047 | In particular, two proteins, CD2-associated protein and nephrin, have been identified as critical podocyte proteins that are both required for normal glomerular filtration. |