Gene Pair Information
Gene Pair: WT1, PAX2
Related Sentences
| # | PMID | Sentence |
| 1 | 9916932 | WT1 and PAX-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial sclerosis. |
| 2 | 9916932 | One target gene of WT1 is PAX2, the expression of which is down-regulated in podocytes during early stages of nephrogenesis. |
| 3 | 9916932 | We demonstrate that WT1 mislocalization is associated with abnormal podocyte expression of PAX2 protein and RNA. |
| 4 | 9916932 | We suggest that persistent expression of PAX2 is likely to result from the loss of WT1 dependent transcriptional repression and may participate in the pathological mechanisms leading to glomerular dysfunction. |
| 5 | 9916932 | Abnormal distribution of WT1 and PAX2 was also observed in isolated diffuse mesangial sclerosis suggesting that a defect in WT1 could also be operative in isolated diffuse mesangial sclerosis. |