Gene Pair Information

Gene Pair: BRCA1, PRL

Related Sentences

# PMID Sentence
1 10329379 Prolactin-dependent up-regulation of BRCA1 expression in human breast cancer cell lines.
2 10329379 We report experimental evidence that BRCA1, a breast and ovarian cancer susceptibility gene, is up-regulated in response to prolactin (PRL) stimulation.
3 10329379 Using competitive RT-PCR, we have shown that PRL induced an increase in BRCA1 mRNA level in MCF-7 and T-47D cell lines at a dose resulting in the maximal enhancement of cell proliferation.
4 10329379 At the protein level, PRL treatment induced a 4-fold increase of BRCA1 protein expression in MCF-7 and a 6-fold increase in T-47D cells, whereas BRCA1 protein expression was not affected by PRL in MCF10a.