Gene Pair Information
Gene Pair: MCC, CDKN1A
Related Sentences
| # | PMID | Sentence |
| 1 | 9321930 | We found that multiple tumor suppressor genes (e.g., p53, DCC, APC, MCC, BRCA1, and WAF1/CIP1) were inactivated at different frequencies via various mechanisms [e.g., loss of heterozygosity (LOH), loss of expression (LOE), mutation, and inactivation by cellular binding protein]. |
| 2 | 9321930 | Several important and novel findings are as following: LOH and LOE of the DCC gene, LOH, LOE, and possible mutation of the APC/MCC genes, LOH of the BRCA1 locus, and mutation of the WAF1/CIP1 gene. |
| 3 | 9321930 | For p53 tumor suppressor gene alone, multiple inactivation mechanisms (i.e., LOH, LOE, mutation, and amplification of the cellular inactivating protein MDM2) were identified. |
| 4 | 9321930 | In addition, we identified a number of novel mechanisms of tumor suppressor gene inactivation, in prostate cancer such as loss of mRNA expression of the DCC, APC, MCC and p53 gene, and mutator phenotype. |
| 5 | 9321930 | When we analyzed the relationship between DCC loss of expression and 12-LOX elevation in prostate cancer pati |