Gene Pair Information
Gene Pair: NME1, BRCA1
Related Sentences
| # | PMID | Sentence |
| 1 | 7852187 | Using seven polymorphic markers on chromosome 17q21, D17S250, ERBB2, THRA1, D17S579, D17S588, GIP and NME1, linkage to BRCA1 was analyzed. |
| 2 | 8406509 | Localization of a second NM23 gene, NME2, to chromosome 17q21-q22. |
| 3 | 8406509 | NM23 is a candidate tumor suppressor protein and has recently been identified as an NDP kinase. |
| 4 | 8406509 | Two NM23 genes, NME1 and NME2, that code for the A and B chains of the kinase, respectively, have been cloned. |
| 5 | 8406509 | The NME2 gene was mapped to the chromosome region 17q21-q22, the same region in which the NME1 gene has been localized. |
| 6 | 8406509 | This region is linked to the early onset breast/ovarian locus (BRCA1) and allelic deletions of NME1 have been associated with metastatic potential of colorectal carcinomas. |
| 7 | 8460637 | THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21. |
| 8 | 8460637 | In order to pinpoint the locale of the gene for early-onset familial breast and ovarian cancer (BRCA1), polymorphisms were developed within the locus for thyroid hormone receptor alpha (THRA1) and for several anonymous sequences at chromosome 17q12-q21. |
| 9 | 8460637 | Gene mapping in extended families with inherited, early-onset breast and ovarian cancer indicates that BRCA1 is distal to THRA1 and proximal to D17S183 (SCG43), an interval of < 4 cM. |
| 10 | 8460637 | This locale excludes HER2, THRA1, WNT3, HOX2, NGFR, PHB, COLIA1, NME1, and NME2 as candidates for BRCA1 but does not exclude RARA or EDH17B. |
| 11 | 9408751 | Chromosome 17 contains at least four genes implicated in breast cancer (TP53, ERBB2 (Her2/neu), BRCA1, and NM23), as well as other putative tumor suppressor genes and oncogenes implicated in loss of heterozygosity or allelic imbalance studies. |