Gene Pair Information
Gene Pair: PAG1, BRCA1
Related Sentences
| # | PMID | Sentence |
| 1 | 9538157 | BRCA1 splice variants BRCA1a and BRCA1b associate with CBP co-activator. |
| 2 | 9538157 | Previously, we have characterized two new BRCA1 splice variants BRCA1a/p110 and BRCA1b/p100. |
| 3 | 9538157 | In the present study, the carboxy-terminal domain of transcription factor CBP interacts both in vivo and in vitro with full length BRCA1a and BRCA1b proteins as demonstrated by mammalian two- hybrid assays, co-immunoprecipitation/western blot studies, GST binding assays and histone acetyl transferase (HAT) assays of BRCA1 immunoprecipitates from human breast cancer cells. |
| 4 | 9538157 | Our results suggest that one of the mechanisms by which BRCA1 proteins function is through recruitment of CBP associated HAT/FAT (transcription factor acetyl-transferase) activity for acetylation of either themselves or general transcription factors or both to specific promoters resulting in transcriptional activation. |