Gene Pair Information
Gene Pair: RB1, BRCA1
Related Sentences
| # | PMID | Sentence |
| 1 | 7981072 | By these means we have excluded involvement of Rb1 and BRCA1 on chromosomes 13q and 17q respectively. |
| 2 | 7981072 | The MDM2 oncogene on chromosome 12q was considered to be the prime candidate as MDM2 is amplified in sarcomas and the MDM2 product binds to p53. |
| 3 | 7981072 | Furthermore, p53 mutation and amplification of MDM2 have been shown to be mutually exclusive events in tumour development. |
| 4 | 8741802 | Examples include the RB1 gene for retinoblastoma; the WT1 gene for Wilms' tumor; germline p53 mutations in families with the Li-Fraumeni syndrome; the NF1 and NF2 genes for neuroblastomatosis, types 1 and 2; the VHL gene for renal cancer and other tumors associated with Von Hippel-Lindau disease; the APC gene for adenomatous polyposis coli; the BRCA1 gene for hereditary breast and ovarian cancer; and the mismatch repair genes for colon and other common cancers. |