Ignet

Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.

An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank	Degree centrality	Eigenvector centrality	Closeness centrality	Betweenness centrality
1	IFNG		IFNG	SOD1
2	INS		INS	INS
3	SOD1		TNF	IFNG
4	TNF		CD4	NPHS1
5	NPHS1		NPHS1	CD4
6	CD4		IL6	ERBB2
7	CD8A		IL1B	AKT1
8	IL2		IL10	CD8A
9	IL6		STAT1	HSPD1
10	IL1B		CD8A	IL6
11	IL10		IL12A	TNF
12	NPHS2		IL4	IGFALS
13	IDDM2		IL2	IL2
14	HLA-A		IL17A	HLA-A
15	IL4		IDDM2	VEGFA
16	IL12A		TGFB1	EGFR
17	SYNPO		TBX21	NPHS2
18	STAT1		CXCL10	CD274
19	VEGFA		IL1A	ALB
20	CXCL10		SOD1	COL1A1
21	ALB		NPHS2	PTH
22	IL17A		IL8	SYNPO
23	AGT		IL18	PIK3CA
24	TGFB1		CD14	SYNPO2
25	ERBB2		IGF1	REN
26	REN		CSF2	IDDM2
27	IGF1		STAT3	CDK5
28	TBX21		IL17D	TP53
29	AKT1		FOXP3	IGF1
30	IL1A		IRF1	AGT
31	IGFALS		TH1L	DMD
32	MAPK1		CXCR3	FAS
33	IL8		CCL5	SMN1
34	WT1		IFNA1	MKI67
35	NFE2L2		IL22	BRCA1
36	EGFR		IL12B	STAT3
37	COL1A1		IL13	MAPT
38	TP53		IFNGR1	MAPK1
39	CD14		CCL2	FUS
40	IFNA1		TLR4	IL4
41	CSF2		IL2RA	MARCH8
42	CD86		NOS2A	WT1
43	IL18		CTLA4	RPS27A
44	IL17D		FAS	TF
45	CASP3		ALB	IL12A
46	JUN		VEGFA	IL10
47	CCL2		NFKB1	ERVWE1
48	TGFA		IFNB1	JUP
49	ACTN4		CASP3	RSL1D1
50	MAPK8		SLC11A1	EPO