Ignet

Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.

An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank	Degree centrality	Eigenvector centrality	Closeness centrality	Betweenness centrality
1	IFNG		IFNG	SOD1
2	COX8A		INS	INS
3	PTGS1		TNF	IFNG
4	PTGS2		IL6	NPHS1
5	INS		COX8A	CD4
6	TNF		PTGS1	ERBB2
7	SOD1		PTGS2	AKT1
8	CISH		IL1B	CD8A
9	CRP		IL10	HSPD1
10	NPHS1		CD4	TNF
11	IL6		CD8A	IL6
12	CD4		NPHS1	IGFALS
13	IL1B		IL4	IL2
14	IL10		IL17A	HLA-A
15	CD8A		IL2	VEGFA
16	IL2		CXCL10	EGFR
17	NPHS2		STAT3	NPHS2
18	IL17A		STAT1	CD274
19	MAP1LC3A		MAP1LC3A	ALB
20	IDDM2		IL12A	COL1A1
21	HLA-A		IL8	PTH
22	IL4		NFKB1	SYNPO
23	STAT3		CCL2	PIK3CA
24	CXCL10		TGFB1	SYNPO2
25	IL12A		FOXP3	REN
26	SYNPO		MAPK1	IDDM2
27	SQSTM1		CD274	CDK5
28	STAT1		AKT1	TP53
29	CCL2		PIK3CA	IGF1
30	ALB		IL17D	AGT
31	VEGFA		IL1A	DMD
32	AGT		IL18	FAS
33	MAPK1		TBX21	SMN1
34	TGFB1		HMGB1	MKI67
35	ERBB2		CSF2	BRCA1
36	IL8		SQSTM1	STAT3
37	HMGB1		NPHS2	MAPT
38	REN		IDDM2	MAPK1
39	AKT1		IL2RA	FUS
40	NFKB1		IRF1	ACTN4
41	IGF1		PDCD1	IL4
42	TBX21		HLA-A	MARCH8
43	IL1A		TLR4	WT1
44	PIK3CA		BECN1	RPS27A
45	IL17D		GZMB	TF
46	IGFALS		TP53	IL12A
47	BECN1		NOS2A	IL10
48	WT1		FASLG	ERVWE1
49	RB1		CXCL9	JUP
50	NFE2L2		CASP3	RSL1D1