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Gene Information
Gene symbol: CASP3
Gene name: caspase 3, apoptosis-related cysteine peptidase
HGNC ID: 1504
Synonyms: CPP32, CPP32B, Yama, apopain
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MAPK1 | 1 hits |
| 2 | MAPK14 | 1 hits |
| 3 | SMAD7 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11560950 | Apoptosis in podocytes induced by TGF-beta and Smad7. |
| 2 | 11560950 | TGF-beta1 and Smad7 each induce apoptosis in podocytes, and their coexpression has an additive effect. |
| 3 | 11560950 | Activation of p38 MAP kinase and caspase-3 is required for TGF-beta-mediated apoptosis, but not for apoptosis induced by Smad7. |
| 4 | 11560950 | Unlike TGF-beta, Smad7 inhibits nuclear translocation and transcriptional activity of the cell survival factor NF-kappaB. |