- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: AIM2
Gene name: absent in melanoma 2
HGNC ID: 357
Synonyms: PYHIN4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ANKRD22 | 1 hits |
| 2 | CASP1 | 1 hits |
| 3 | HMGB1 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | IL1A | 1 hits |
| 6 | IL1B | 1 hits |
| 7 | IL6 | 1 hits |
| 8 | MMP9 | 1 hits |
| 9 | NFKB1 | 1 hits |
| 10 | NLRP3 | 1 hits |
| 11 | NOD1 | 1 hits |
| 12 | NOD2 | 1 hits |
| 13 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 27806943 | Incubation of the chorioamniotic membranes with HMGB1 1) induced the release of mature IL-1beta and IL-6; 2) upregulated the mRNA expression of the pro-inflammatory mediators NFKB1, IL6, TNF, IL1A, IFNG, and HMGB1 receptors RAGE and TLR2; 3) upregulated the mRNA expression of the inflammasome components NLRP3 and AIM2 as well as NOD proteins (NOD1 and NOD2); 4) increased the protein concentrations of NLRP3 and NOD2; 5) increased the concentration of caspase-1 and the quantity of its active form (p20); and 6) upregulated the mRNA expression and active form of MMP-9. |
| 2 | 25219326 | Molecular landscape of T cell-mediated rejection in human kidney transplants: prominence of CTLA4 and PD ligands. |
| 3 | 25219326 | CTLA4, CD28, IFNG), macrophages (e.g. |
| 4 | 25219326 | PDL1, CD86, SLAMF8, ADAMDEC1), B cells (e.g. |
| 5 | 25219326 | CD72, BTLA) and IFNG-treated macrophages (e.g. |
| 6 | 25219326 | ANKRD22, AIM2). |
| 7 | 25219326 | In pathway analysis, the top pathways included T cell receptor signaling and CTLA4 costimulation. |
| 8 | 25219326 | The prominence of inhibitors like CTLA4 and PDL1 raises the possibility of active negative controls within the rejecting tissue. |