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Gene Information

Gene symbol: APEX1

Gene name: APEX nuclease (multifunctional DNA repair enzyme) 1

HGNC ID: 587

Synonyms: APE, REF1, HAP1, APX, APEN, REF-1, APE-1

Related Genes

#	Gene Symbol	Number of hits
1	CAMP	1 hits
2	DEFB1	1 hits

Related Sentences

#	PMID	Sentence
1	25815330	Our aim was to investigate the effects of hyperthermia, ultraviolet A rays (UVA), and ultraviolet C rays (UVC) as well as glucose and ascorbic acid (AA) on the regulation of human β-defensin 1 (DEFB1), cathelicidin (CAMP), and interferon-γ (IFNG) genes in normal human keratinocytes (NHK).
2	25815330	Our aim was to investigate the effects of hyperthermia, ultraviolet A rays (UVA), and ultraviolet C rays (UVC) as well as glucose and ascorbic acid (AA) on the regulation of human β-defensin 1 (DEFB1), cathelicidin (CAMP), and interferon-γ (IFNG) genes in normal human keratinocytes (NHK).
3	25815330	We found that AA is a more potent APE for DEFB1 than glucose in NHK.
4	25815330	We found that AA is a more potent APE for DEFB1 than glucose in NHK.
5	25815330	Glucose but not AA is an APE for CAMP.
6	25815330	Glucose but not AA is an APE for CAMP.
7	25815330	AA-dependent DEFB1 upregulation below 20 mM predicts in vitro antimicrobial activity as well as glucose- and AA-dependent CAMP and IFNG upregulation.
8	25815330	AA-dependent DEFB1 upregulation below 20 mM predicts in vitro antimicrobial activity as well as glucose- and AA-dependent CAMP and IFNG upregulation.
9	25815330	UVC upregulates CAMP and DEFB1 genes but UVA only upregulates the DEFB1 gene.
10	25815330	UVC upregulates CAMP and DEFB1 genes but UVA only upregulates the DEFB1 gene.
11	25815330	Our results suggest that glucose upregulates CAMP in an IFN-γ-independent manner.
12	25815330	Our results suggest that glucose upregulates CAMP in an IFN-γ-independent manner.