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Gene Information

Gene symbol: APOL6

Gene name: apolipoprotein L, 6

HGNC ID: 14870

Synonyms: APOL-VI, APOLVI

Related Genes

#	Gene Symbol	Number of hits
1	APOL1	1 hits
2	APOL2	1 hits

Related Sentences

#	PMID	Sentence
1	24901046	Apolipoprotein L1 and apolipoprotein L6 have been recently described as novel pro-death BH3-only proteins that are also capable of regulating autophagy.
2	24901046	In an in-silico screening to discover novel putative BH3-only proteins, we identified yet another member of the apolipoprotein L family, apolipoprotein L2 (ApoL2), as a BH3 motif-containing protein.
3	24901046	ApoL2 has been suggested to behave as a BH3-only protein and mediate cell death induced by interferon-gamma or viral infection.
4	24901046	As previously described, we observed that ApoL2 protein was induced by interferon-gamma.
5	24901046	ApoL2 did not sensitize or protect cells from overexpression of the BH3-only proteins Bmf or Noxa.
6	24901046	We could, however, detect a weak interaction between ApoL2 and Bcl-2 by immunoprecipitation of the former, suggesting a role of ApoL2 in a Bcl-2-regulated process like autophagy.
7	24901046	However, in contrast to what has been described about its homologs ApoL1 and ApoL6, ApoL2 did not regulate autophagy.
8	24901046	Apolipoprotein L1 and apolipoprotein L6 have been recently described as novel pro-death BH3-only proteins that are also capable of regulating autophagy.
9	24901046	In an in-silico screening to discover novel putative BH3-only proteins, we identified yet another member of the apolipoprotein L family, apolipoprotein L2 (ApoL2), as a BH3 motif-containing protein.
10	24901046	ApoL2 has been suggested to behave as a BH3-only protein and mediate cell death induced by interferon-gamma or viral infection.
11	24901046	As previously described, we observed that ApoL2 protein was induced by interferon-gamma.
12	24901046	ApoL2 did not sensitize or protect cells from overexpression of the BH3-only proteins Bmf or Noxa.
13	24901046	We could, however, detect a weak interaction between ApoL2 and Bcl-2 by immunoprecipitation of the former, suggesting a role of ApoL2 in a Bcl-2-regulated process like autophagy.
14	24901046	However, in contrast to what has been described about its homologs ApoL1 and ApoL6, ApoL2 did not regulate autophagy.