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Gene Information

Gene symbol: ARHGEF2

Gene name: Rho/Rac guanine nucleotide exchange factor (GEF) 2

HGNC ID: 682

Synonyms: LFP40, GEF-H1, KIAA0651, P40

Related Genes

# Gene Symbol Number of hits
1 IL12A 1 hits

Related Sentences

# PMID Sentence
1 9656442 Influence of IL-12 on interferon-gamma production by bovine leucocyte subsets in response to bovine respiratory syncytial virus.
2 9656442 The cytokine IL-12 is a key molecule in the regulation of CD4+ T cell development and specifically potentiates the development of T helper 1 responses in mouse and man.
3 9656442 Here the 2A was flanked by sequences encoding the p35 and p40 polypeptides of the heterodimeric cytokine to mediate their cleavage.
4 9656442 The presence of IL-12 markedly influenced the level of IFNg secreted by these cells, and although IL-12 induced IFNg production in the absence of antigenic stimulation, IFNg production was accelerated and augmented in response to IL-12 and antigen.
5 9656442 Analysis of the T cell subsets by flow cytometry showed that CD4+ T cells comprised the largest contributors to IFNg production.