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Gene Information
Gene symbol: BTLA
Gene name: B and T lymphocyte associated
HGNC ID: 21087
Synonyms: BTLA1, CD272
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD69 | 1 hits |
| 2 | CD72 | 1 hits |
| 3 | CXCR5 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | PDCD1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 27531854 | These cells were the major source of IL21 in tumors and represented about 10% of the CD4+ T-cell population at levels comparable with the TFH cells present in lymph nodes. |
| 2 | 27531854 | However, these TFH-like cells displayed a unique CXCR5-PD-1lo/-BTLA-CD69hi tissue-resident phenotype with substantial IFNγ production, which differed from the phenotype of TFH cells. |
| 3 | 27531854 | Toll-like receptor 4 (TLR4)-elicited innate monocyte inflammation was important for IL21+ TFH-like cell induction in tumors, and activation of STAT1 and STAT3 was critical for TFH-like cell polarization in this process. |
| 4 | 25219326 | Molecular landscape of T cell-mediated rejection in human kidney transplants: prominence of CTLA4 and PD ligands. |
| 5 | 25219326 | CTLA4, CD28, IFNG), macrophages (e.g. |
| 6 | 25219326 | PDL1, CD86, SLAMF8, ADAMDEC1), B cells (e.g. |
| 7 | 25219326 | CD72, BTLA) and IFNG-treated macrophages (e.g. |
| 8 | 25219326 | ANKRD22, AIM2). |
| 9 | 25219326 | In pathway analysis, the top pathways included T cell receptor signaling and CTLA4 costimulation. |
| 10 | 25219326 | The prominence of inhibitors like CTLA4 and PDL1 raises the possibility of active negative controls within the rejecting tissue. |