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Gene Information
Gene symbol: CADM1
Gene name: cell adhesion molecule 1
HGNC ID: 5951
Synonyms: NECL2, ST17, BL2, SYNCAM, IGSF4A, Necl-2, SYNCAM1, RA175
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ESAM | 1 hits |
| 2 | PECAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 26956486 | We found that the cell surface molecule platelet endothelial cell adhesion molecule-1 (PECAM-1) facilitated noncanonical (Smad-independent) TGF-β signaling in T cells. |
| 2 | 26956486 | T cells isolated from PECAM-1(-/-) mice demonstrated relative insensitivity to the TGF-β-dependent inhibition of interferon-γ (IFN-γ) production, granzyme B synthesis, and cellular proliferation. |
| 3 | 26956486 | Co-incubation of T cells with TGF-β and a T cell-activating antibody resulted in PECAM-1 phosphorylation on an immunoreceptor tyrosine-based inhibitory motif (ITIM) and the recruitment of the inhibitory Src homology 2 (SH2) domain-containing tyrosine phosphatase-2 (SHP-2). |