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Gene Information
Gene symbol: CBX3
Gene name: chromobox homolog 3
HGNC ID: 1553
Synonyms: HP1Hs-gamma
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | FOXP3 | 1 hits |
| 4 | IL2RA | 1 hits |
| 5 | KLRK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 28220815 | Here, we demonstrate that in CD8+ T cells, Cbx3/HP1γ insufficiency leads to chromatin remodeling accompanied by enhanced Prf1, Gzmb and Ifng expression. |
| 2 | 28220815 | In tumors obtained from Cbx3/HP1γ-insufficient mice or wild type mice treated with Cbx3/HP1γ-insufficient CD8+ T cells, there is an increase of CD8+ effector T cells expressing the stimulatory receptor Klrk1/NKG2D, a decrease in CD4+ CD25+ FOXP3+ regulatory T cells (Treg cells) as well as CD25+ CD4+ T cells expressing the inhibitory receptor CTLA4. |